Last name Isaias Manuel (Isaias Manuel 
) , around the globe, is a very rare family name. The last name Isaias Manuel is habitual in Latin America and the Caribbean, particularly Chile, where it is a rare surname. More prevalently, Isaias Manuel is the forename as well as the last name.
| VARIANT | COUNTRY |
|---|---|
| Isaias Manuel | Panama, Spain, Peru, Ecuador, Chile |